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Impact of seasonal cycle on rheumatoid arthritis based on genetic and epigenetic mechanisms

5 Sept 2025

Abstract excerpt

Rheumatoid arthritis is an autoimmune disease characterized by chronic inflammation and progressive joint destruction. Genetic and environmental risk factors contribute to the development of rheumatoid arthritis (RA). Among environmental factors, seasonal cycles are reported to impact the clinical phenotypes in RA, with rheumatic flares being aggravated during the winter season. Gaining insight into the seasonal...

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PMID: 40977678
DOI: 10.3389/fimmu.2025.1601767

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