Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetics in the pathogenesis of RA.

Seminars in immunopathology - 1 Jun 2017

Ospelt Caroline, Gay Steffen, Klein Kerstin

Abstract excerpt

Epigenetic modifications can stably alter gene expression and have been shown to be important in the maintenance of cell type-specific functions as well as in cell differentiation, e.g., in T and B cell maturation. In RA, alterations in DNA methylation, histone modifications, and microRNA expression have been found in immune as well as in stromal cells. These changes in the epigenome in RA patients influence key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histones
Share to MicroRNAs
Share to Synovial Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arthritis, Rheumatoid

Share to Biomarkers

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Fibroblasts

Source

Identifiers

PMID: 28324153
DOI: 10.1007/s00281-017-0621-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetics in the pathogenesis of RA.PMID 28324153Read ↗

Epigenetic Changes in the Pathogenesis of Rheumatoid ArthritisSemantic proximity Read ↗

The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic LandscapeSemantic proximity Read ↗

Epigenetic contributions in the development of rheumatoid arthritisSemantic proximity Read ↗

What can we learn from epigenetics in the year 2009?Semantic proximity Read ↗

Epigenetics in rheumatoid arthritisSemantic proximity Read ↗

DNA Methylation-Governed Gene Expression in Autoimmune ArthritisSemantic proximity Read ↗

Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritisSemantic proximity Read ↗

Epigenetics in rheumatoid arthritis; fibroblast‐like synoviocytes as an emerging paradigm in the pathogenesis of the diseaseSemantic proximity Read ↗

Epigenetic Regulation Mediated by Methylation in the Pathogenesis and Precision Medicine of Rheumatoid ArthritisSemantic proximity Read ↗

DNA Methylation of T Lymphocytes as a Therapeutic Target: Implications for Rheumatoid Arthritis EtiologySemantic proximity Read ↗

Epigenetic Regulation in the Pathogenesis of Sjögren Syndrome and Rheumatoid ArthritisSemantic proximity Read ↗

Epigenetic alterations in rheumatoid arthritis fibroblast-like synoviocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.