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ANXA6 Overexpression Causes Abnormal Decidual Macrophage-Trophoblast Crosstalk in Recurrent Spontaneous Abortion

11 Aug 2025

Abstract excerpt

ANXA6 is involved in numerous biological processes; however, its association with recurrent spontaneous abortion (RSA) remains poorly understood.In this study, we observed significant upregulation of ANXA6 expression in decidual macrophages from RSA patients.Functional analysis revealed that ANXA6 overexpression enhanced reactive oxygen species (ROS) generation and reduced mitochondrial membrane potential,...

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Share to Ectopic Pregnancy Diagnosis and Management
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Identifiers

PMID: 40959268
DOI: 10.7150/ijbs.111791

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