Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy

20 Aug 2021

Abstract excerpt

One of the hallmarks of placental dysfunction is the increase of oxidative stress. This process, along with the overexpression of the inflammasome, creates a downward spiral that can lead to a series of severe pregnancy complications. Ferroptosis is a form of iron-mediated cell death involving the accumulation of reactive oxygen species, lipid peroxides. In this study, the rats’ model of oxidative stress abortion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34490257
DOI: 10.3389/fcell.2021.707959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse PregnancyPMID 34490257Read ↗

Role of ferroptosis in pregnancy related diseases and its therapeutic potentialSemantic proximity Read ↗

Ferroptosis in Obstetrical and Gynecological Diseases: A Mini ReviewSemantic proximity Read ↗

The emerging role of ferroptosis in female reproductive disordersSemantic proximity Read ↗

The Emerging Roles of Ferroptosis and NETosis in Pregnancy Complications: Insights into Preeclampsia and Gestational Diabetes MellitusSemantic proximity Read ↗

Ferroptosis and Its Emerging Role in Pre-EclampsiaSemantic proximity Read ↗

miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsiaSemantic proximity Read ↗

Impact of ferroptosis on preeclampsia: A reviewSemantic proximity Read ↗

CX43 inhibit ferroptosis in villous and decidua tissues of patients with unexplained recurrent spontaneousabortion through the Nrf2/GPX4 signaling pathwaySemantic proximity Read ↗

Oxidative Stress in Placenta: Health and DiseasesSemantic proximity Read ↗

Focus on Cell Apoptosis, Pyroptosis and Ferroptosis to Explore Strategic Breakthrough for GDMSemantic proximity Read ↗

PLA2G6 guards placental trophoblasts against ferroptotic injurySemantic proximity Read ↗

The regulated cell death at the maternal-fetal interface: beneficial or detrimental?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.