Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessing ADME gene coverage: An observational study on chloroquine therapy for COVID-19.

Medicine - 12 Sept 2025

Zaid Nabil, Benchikhi Lamyaa, El Abboudi Naoual, Khalki Loubna, Badad Oussama, Limami Youness, Naya Abdallah, Oudghiri Mounia, Himmi Banacer, Zaid Younes

Abstract excerpt

This observational study aimed to compare various genotyping and enrichment platforms to determine the most comprehensive coverage for genome-wide association studies, specifically targeting new therapeutic approaches against coronaviruses using chloroquine. Pharmacogenomic studies have become essential for understanding individual drug responses, and optimal platform selection is critical for identifying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloroquine
Share to COVID-19

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to COVID-19 Drug Treatment

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Pharmacogenetics

Share to Polymorphism, Single Nucleotide

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 40958299
DOI: 10.1097/MD.0000000000044340
PMCID: PMC12440472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessing ADME gene coverage: An observational study on chloroquine therapy for COVID-19.PMID 40958299Read ↗

Coverage Rate of ADME Genes: Application to CYP2C8, CYP2D6 and CYP3A Genes for Personalized Chloroquine Treatment Against CoronavirusSemantic proximity Read ↗

Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.Semantic proximity Read ↗

Pharmacogenomics to Drive COVID-19 Therapy for Best Outcome in a Low Resource SettingSemantic proximity Read ↗

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics.Semantic proximity Read ↗

Genetic Profiles in Pharmacogenes Indicate Personalized Drug Therapy for COVID-19Semantic proximity Read ↗

ClinPharmSeq: A targeted sequencing panel for clinical pharmacogenetics implementation.Semantic proximity Read ↗

<i>G6PD</i> variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19Semantic proximity Read ↗

Pharmacogenomic Diversity in Psychiatry: Challenges and Opportunities in AfricaSemantic proximity Read ↗

G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.Semantic proximity Read ↗

Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screensSemantic proximity Read ↗

Pharmacogenetics Approach for the Improvement of COVID-19 TreatmentSemantic proximity Read ↗

AI-Driven Pharmacovigilance and Molecular Profiling of Fluoroquinolone-Associated Cardiotoxicity in the UAE: A Geospatial and Machine Learning Analysis with Structural Modification Strategies (2018-2023)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.