Article
Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes.
Diabetologia - 1 May 2022
Su Mei-Hsin, Shih Ying-Hsiu, Lin Yen-Feng, Chen Pei-Chun, Chen Chia-Yen, Hsiao Po-Chang, Pan Yi-Jiun, Liu Yu-Li, Tsai Shih-Jen, Kuo Po-Hsiu, Wu Chi-Shin, Huang Yen-Tsung, Wang Shi-Heng
Abstract excerpt
AIMS/HYPOTHESIS: Psychiatric disorders, such as schizophrenia (SCZ), major depressive disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes. However, the mechanisms underlying such comorbidity are understudied. This study explored the familial aggregation of common psychiatric disorders and type 2 diabetes by testing family history association, and investigated the shared genetic...
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