Article
[Understanding biology to identify new therapeutic targets beyond chemotherapy in ovarian granulosa cell tumors].
Bulletin du cancer - 1 Mar 2026
Endale Ahanda Sil, Lainé Alexandra, Hanvic Brunhilde, Verdet Quentin, Ikhlef Léa, De Palma Antonella, Fieuws Sarah, Ferrari Anthony, Cumunel Eric, Chopin Nicolas, Rousset-Jablonski Christine, Rossi Léa, Meeus Pierre, Serre Anne-Agathe, Treilleux Isabelle, Ray-Coquard Isabelle, Le Saux Olivia
Abstract excerpt
Granulosa cell tumors (GCTs) are rare ovarian neoplasms, accounting for 2-5% of all ovarian cancers. Two histological types have been described: juvenile (JGCT) and adult (AGCT), the latter accounting for around 95% of the GCTs. AGCTs are mostly diagnosed at an early stage and commonly have a good prognosis. However, GCTs tend to be associated with late recurrence in about a third of cases which are a major...
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