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Article

Causal Association Between Epidermal Growth Factor and Laryngeal/Oropharyngeal Cancer: A 2-Sample Mendelian Randomization Analysis.

The Journal of craniofacial surgery - 1 Sept 2025

Xu Jing, Wang Daohe, Wang Jun

Abstract excerpt

The human epidermal growth factor (EGF)-related proteins are thought to play a key role in the pathogenesis of laryngeal cancer (LC) and oropharyngeal cancer (OPC). The aim of this study was to investigate the potential causal relationship between them. A 2-sample Mendelian randomization (MR) analysis utilizing genome-wide association studies (GWAS) data uniquely evaluated causal relationships between EGF-related...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40899836
DOI: 10.1097/SCS.0000000000011794

Genes

EGF
EGFR
EPS15L1
MEGF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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