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Article

Genetically predicted plasma metabolites mediate the relation between inflammatory factors and Meniere's disease.

Brazilian journal of otorhinolaryngology - 1 Jan 2026

Wang Jian, Hu Jian-Dao, Qian Jing

Abstract excerpt

OBJECTIVE: Emerging evidence suggests inflammation contributes to Meniere's Disease (MD), a chronic vestibular disorder characterized by vertigo, hearing loss, and tinnitus. However, the causal role of Inflammatory Factors (IFs) and the mediating effects of Plasma Metabolites (PMs) in MD remain unclear. This study investigated bidirectional causality between IFs and MD and evaluated PMs as potential mediators....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41650667
DOI: 10.1016/j.bjorl.2026.101772
PMCID: PMC12906162

Genes

CCL23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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