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Article

Clinical and molecular characterization of patients with juvenile myelomonocytic leukaemia.

British journal of haematology - 1 Nov 2025

Meyer Julia A, Xirenayi Sherin, Werner Juwita, Turakulov Rust, Hechmer Aaron, Abdullaev Zied, Hamdy Nayera, Olshen Adam, Stieglitz Elliot, Hammad Mahmoud, Elhaddad Alaa

Abstract excerpt

Juvenile myelomonocytic leukaemia (JMML) is a rare haematological malignancy caused by mutations in the Ras signalling pathway. Next-generation sequencing (NGS) and DNA methylation profiling used for diagnostic and risk stratification purposes are now standard of care in Europe and the United States for patients with JMML. To better understand how implementing these types of technologies would impact the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myelomonocytic, Juvenile

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Identifiers

PMID: 40887320
DOI: 10.1111/bjh.70106
PMCID: PMC13256139

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