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Article

MYH6-Cre Insertion Accelerates Cardiac Phenotype in Dystrophic D2-mdx Mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Jul 2025

Hawkins India K, Phi Trung, Mitchell Joshua, Corwin Frank, Mauro Adolfo G, Salloum Fadi N, Raucci Frank J

Abstract excerpt

Duchenne Muscular Dystrophy (DMD) is a progressive muscular degenerative disease that is recessively inherited through the X chromosome. Various mutations in the dystrophin gene lead to noticeable muscle weakness. The effects on skeletal and cardiac tissue result in progressive immobility and cardiac dysfunction, respectively. There are several murine models used to study DMD; however, there are still limitations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40879110
DOI: 10.1096/fj.202500792R
PMCID: PMC12257423

Genes

DMD
MYH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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