Article
Cardiac Involvement in Dystrophin-Deficient Females: Current Understanding and Implications for the Treatment of Dystrophinopathies.
Genes - 8 Jul 2020
Lim Kenji Rowel Q, Sheri Narin, Nguyen Quynh, Yokota Toshifumi
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive condition caused primarily by out-of-frame mutations in the dystrophin gene. In males, DMD presents with progressive body-wide muscle deterioration, culminating in death as a result of cardiac or respiratory failure. A milder form of DMD exists, called Becker muscular dystrophy (BMD), which is typically caused by in-frame dystrophin gene mutations....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.