Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic correlation and causal relationships between autoimmune thyroid disease and major depressive disorders.

Acta neuropsychiatrica - 26 Aug 2025

Yu Yang, Zhong Yingshuo, Chen Yingzi, Du Peng, Miao Congqing, Lu Dechuan

Abstract excerpt

BACKGROUND: Autoimmune thyroid disease (AITD) and major depressive disorder (MDD) are common genetic diseases. The comorbidity of AITD and MDD has been widely demonstrated by large amounts of epidemiological studies. However, the genetic architectures of the comorbidity remain unknown. METHODS: We use large-scale GWAS summary data and novel genetic statistical methods to assess the genetic correlation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Comorbidity
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Major Depressive Disorder

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Thyroid Diseases

Share to Thyroiditis, Autoimmune

Source

Open in PubMed Open full text

Identifiers

PMID: 40855782
DOI: 10.1017/neu.2025.10033
PMCID: PMC13130264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic correlation and causal relationships between autoimmune thyroid disease and major depressive disorders.PMID 40855782Read ↗

Shared genetic architecture and pathways linking major depressive disorder and autoimmune thyroid disease: insights from common and rare variants.Semantic proximity Read ↗

Shared genetic links between hypothyroidism and psychiatric disorders: evidence from a comprehensive genetic analysis.Semantic proximity Read ↗

Dissecting the Genetic Relationship Between Severe Mental Disorders and Autoimmune DiseasesSemantic proximity Read ↗

Dissecting the genetic relationship between severe mental disorders and autoimmune diseases.Semantic proximity Read ↗

Causes and consequences of major depressive disorder: An encompassing Mendelian randomization studySemantic proximity Read ↗

Investigating the shared genetic links between hypothyroidism and psychiatric disorders: a large-scale genomewide cross-trait analysis.Semantic proximity Read ↗

Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK BiobankSemantic proximity Read ↗

Genetic Associations Between Stress-Related Disorders and Autoimmune Disease.Semantic proximity Read ↗

Shared Genetic Liability Between Major Depressive Disorder and Atopic Diseases.Semantic proximity Read ↗

Investigating pleiotropy between depression and autoimmune diseases using the UK BiobankSemantic proximity Read ↗

Comorbidity Alters the Genetic Relationship Between Anxiety Disorders and Major Depression.Semantic proximity Read ↗

Phenome-wide investigation of bidirectional causal relationships between major depressive disorder and common human diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.