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Integrative Multi-Omics Analysis Reveals Critical Molecular Networks Linking Intestinal-System Diseases to Colorectal Cancer Progression

21 Nov 2024

Abstract excerpt

Background/Objectives: Colorectal cancer (CRC) frequently co-occurs with intestinal system diseases (ISDs), yet their molecular interplay remains poorly understood. We employed a comprehensive bioinformatics approach to elucidate shared genetic signatures and pathways between CRC and ISDs. Methods: We systematically analyzed 12 microarray and RNA-seq datasets encompassing 989 samples across seven ISDs and CRC....

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Colorectal Cancer Screening and Detection
Genetic factors in colorectal cancer
Helicobacter pylori-related gastroenterology studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39767563
DOI: 10.3390/biomedicines12122656

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