Article
Multi-omics analysis to identify driving factors in colorectal cancer.
Epigenomics - 1 Sept 2020
Xu Xi, Gong Chaoju, Wang Yunfeng, Hu Yanyan, Liu Hong, Fang Zejun
Abstract excerpt
Aim: We aim to identify driving genes of colorectal cancer (CRC) through multi-omics analysis. Materials & methods: We downloaded multi-omics data of CRC from The Cancer Genome Atlas dataset. Integrative analysis of single-nucleotide variants, copy number variations, DNA methylation and differentially expressed genes identified candidate genes that carry CRC risk. Kernal genes were extracted from the weighted...
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