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Article

Causal associations between neuroinflammation-related genes and intracerebral hemorrhage: an integrated study of Mendelian Randomization and gene functional analysis.

The International journal of neuroscience - 1 Feb 2026

Zhou Quanming, Wu Shejuan, Kang Yuanbao

Abstract excerpt

AIM: Intracerebral hemorrhage (ICH) is a life-threatening stroke subtype where neuroinflammation plays a crucial role. However, the genetic basis for neuroinflammation in ICH remains unclear. METHODS: This study used Mendelian Randomization (MR) to investigate the causal impact of neuroinflammation-related genes on ICH risk. A two-sample MR analysis was conducted using genetic variants from large-scale...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40601346
DOI: 10.1080/00207454.2025.2529232

Genes

CHUK
CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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