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Article

Platelet mitochondrial transfer via extracellular vesicles modulates neutrophil phenotype and function.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2025

Allan Harriet E, Dark Nicola, Vulliamy Paul, Crescente Marilena, Maffucci Tania, Armstrong Paul C, Ferreira Plinio, Warner Timothy D

Abstract excerpt

BACKGROUND: Platelet activation causes the release of extracellular vesicles, of which a small proportion contain respiratory competent mitochondria. Mitochondria are integral for energy production and in the regulation of apoptotic pathways; however, the existence of extracellular mitochondria highlights a potential new role in intercellular communication. Indeed, mitochondrial transfer has gained significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40846030
DOI: 10.1016/j.jtha.2025.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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