Article
Neutrophil-derived extracellular vesicles modulate the phenotype of naïve human neutrophils.
Journal of leukocyte biology - 1 Nov 2021
Amjadi Maya F, Avner Benjamin S, Greenlee-Wacker Mallary C, Horswill Alexander R, Nauseef William M
Abstract excerpt
Neutrophils (PMN) regulate inflammation in many ways, including communication with other immune cells via extracellular vesicles (EVs). EVs released by human neutrophils activated with N-formylmethionyl-leucyl-phenylalanine (fMLF) (PMN-fMLF EVs) had an outside-out orientation and contained functionally important neutrophil plasma membrane proteins, including flavocytochrome b558, and enzymatically active granule...
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