Article
Phenotypic Characterization of Acoustically Enriched Extracellular Vesicles from Pathogen-Activated Platelets.
Journal of innate immunity - 1 Jan 2023
Palm Frida, Broman Axel, Marcoux Genevieve, Semple John W, Laurell Thomas L, Malmström Johan, Shannon Oonagh
Abstract excerpt
Extracellular vesicles (EVs) are derived from the membrane of platelets and released into the circulation upon activation or injury. Analogous to the parent cell, platelet-derived EVs play an important role in hemostasis and immune responses by transfer of bioactive cargo from the parent cells. Platelet activation and release of EVs increase in several pathological inflammatory diseases, such as sepsis. We have...
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