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Article

Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function.

Scientific reports - 22 Oct 2020

Ferreira P M, Bozbas E, Tannetta S D, Alroqaiba N, Zhou R, Crawley J T B, Gibbins J M, Jones C I, Ahnström J, Yaqoob P

Abstract excerpt

Platelet-derived extracellular vesicles (PDEVs) are the most abundant amongst all types of EVs in the circulation. However, the mechanisms leading to PDEVs release, their role in coagulation and phenotypic composition are poorly understood. PDEVs from washed platelets were generated using different stimuli and were characterised using nanoparticle tracking analysis. Procoagulant properties were evaluated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33093473
DOI: 10.1038/s41598-020-73005-3
PMCID: PMC7582134

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