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Article

Phenotypic and Spatial Characterization of Tumor-Associated Macrophages in Non-Metastatic Seminoma: Association with Local Tumor Progression.

Medical sciences (Basel, Switzerland) - 14 Aug 2025

Demyashkin Grigory, Shchekin Vladimir, Belokopytov Dmitriy, Borovaya Tatyana, Zaborsky Ivan, Safiullin Kadir, Karyakin Oleg, Krasheninnikov Alexey, Vorobyev Nikolay, Shegay Petr, Kaprin Andrei

Abstract excerpt

Background: Seminoma is the most common subtype of testicular germ cell tumors in young men; however, the contribution of tumor-associated macrophages (TAMs) to disease progression remains insufficiently understood. This study aimed to quantitatively and phenotypically characterize CD68+ and CD163+ TAMs in non-metastatic seminomas (pT1N0M0 and pT2N0M0). Methods: This retrospective, multicenter, cohort,...

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Share to Antigens, CD
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Cell Surface

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Source

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Identifiers

PMID: 40843751
DOI: 10.3390/medsci13030129
PMCID: PMC12371909

Genes

CD163
CD68

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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