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Article

Phenotypical change of tumor-associated macrophages in metastatic lesions of clear cell renal cell carcinoma.

Medical molecular morphology - 1 Mar 2018

Motoshima Takanobu, Miura Yuji, Wakigami Nanako, Kusada Natsuki, Takano Toshimi, Inoshita Naoko, Okaneya Toshikazu, Sugiyama Yutaka, Kamba Tomomi, Takeya Motohiro, Komohara Yoshihiro

Abstract excerpt

Macrophages are the main immune cells of the tumor microenvironment in clear cell renal cell carcinoma (ccRCC). A high density of CD163+ or CD204+ tumor-associated macrophages (TAMs), rather than the density of total TAMs, is known to be linked to poor clinical outcome. In the present study, we investigated the phenotypical differences between the paired primary and metastatic lesions in ccRCC cases. Using...

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Share to Antigens, Differentiation, Myelomonocytic
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD163 Antigen

Share to Lymphatic Metastasis

Share to Neoplasm Metastasis

Share to Receptors, Cell Surface

Share to Scavenger Receptors, Class A

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Source

Identifiers

PMID: 29218457
DOI: 10.1007/s00795-017-0174-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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