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Article

Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma.

Oncotarget - 29 Nov 2016

Dumars Clotilde, Ngyuen Jean-Michel, Gaultier Aurélie, Lanel Rachel, Corradini Nadège, Gouin François, Heymann Dominique, Heymann Marie-Françoise

Abstract excerpt

Osteosarcoma (OS) is the most common bone sarcoma in adolescents, and has poor prognosis. A vicious cycle is established between OS cells and their microenvironment in order to facilitate the tumor growth and cell spreading. The present work aims to better characterize the tumor microenvironment in OS in order to identify new therapeutic targets relating to metastatic process. Tissue microarrays of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27823976
DOI: 10.18632/oncotarget.13055
PMCID: PMC5346643

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