Pangenome-based genome inference using integer programming.

Abstract excerpt

Affordable genotyping methods are essential in genomics. Commonly used genotyping methods primarily support single-nucleotide variants and short indels but neglect structural variants. Additionally, accuracy of read alignments to a reference genome is unreliable in highly polymorphic and repetitive regions, further impacting genotyping performance. Recent works highlight the advantage of pangenome graphs in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Genome, Human
• Share to Genomics