Article

Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival

2021-08-06

Abstract excerpt

Septic patients frequently develop skeletal muscle wasting and weakness, resulting in severe clinical consequences and adverse outcomes. Autophagy is a stress-induced degradative process essential to cell survival. Recent studies have demonstrated that sepsis triggers sustained induction of autophagy in skeletal muscles, although the impact of this enhanced autophagy on sepsis-induced muscle dysfunction remains un...

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Literature Corpus work: e79e4bb4-85ca-54b4-ae7c-31dbb902553d
DOI: 10.1101/2021.08.05.455081

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