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Epithelial characteristics of ovarian clear cell carcinoma at single-cell resolution

5 Aug 2025

Abstract excerpt

Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant epithelial cells in OCCC remain poorly studied. We establish an OCCC-associated transcriptional landscape using single-cell RNA sequencing and investigated the properties of...

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PMID: 40764744
DOI: 10.1038/s42003-025-08617-4

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