Article
Multigeographic clinical assessment of a molecular diagnostic assay for detection of key codons to predict decreased susceptibility or resistance to cephalosporins in Neisseria gonorrhoeae.
Antimicrobial agents and chemotherapy - 5 Dec 2024
Wang Liqin, Li Yamei, Xiu Leshan, Hu Lihua, Huang Jia, Yong Gang, Wang Youwei, Cao Wenling, Yang Yang, Wang Feng, Gu Weiming, Peng Junping
Abstract excerpt
Cephalosporin resistance in Neisseria gonorrhoeae has severely compromised the efficacy of World Health Organization (WHO)-recommended therapies. This study aimed to methodologically evaluate the optimized Six-CodonPlus assay, and additionally conducted a multicenter evaluation to assess its clinical application, especially for predicting antimicrobial resistance (AMR). For methodological evaluation, 397...
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