Article
High precision Neisseria gonorrhoeae variant and antimicrobial resistance calling from metagenomic Nanopore sequencing.
Genome research - 1 Sept 2020
Sanderson Nicholas D, Swann Jeremy, Barker Leanne, Kavanagh James, Hoosdally Sarah, Crook Derrick, Street Teresa L, Eyre David W
Abstract excerpt
The rise of antimicrobial-resistant Neisseria gonorrhoeae is a significant public health concern. Against this background, rapid culture-independent diagnostics may allow targeted treatment and prevent onward transmission. We have previously shown metagenomic sequencing of urine samples from men with urethral gonorrhea can recover near-complete N. gonorrhoeae genomes. However, disentangling the N. gonorrhoeae...
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