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Target enrichment improves culture-independent detection of<i>Neisseria gonorrhoeae</i>direct from sample with Nanopore sequencing

2024-01-10

Abstract excerpt

Multi-drug resistant Neisseria gonorrhoeae infection is a significant public health risk. Rapidly detecting N. gonorrhoeae and antimicrobial resistant (AMR) determinants by metagenomic sequencing of urine is possible, although high levels of host DNA and overgrowth of contaminating species hamper sequencing and limit N. gonorrhoeae genome coverage. We performed Nanopore sequencing of nucleic acid amplification tes...

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Literature Corpus work
ce2fc4e0-8362-5fac-83c8-95b529c2912e
DOI
10.1101/2024.01.09.24301039
Open publication

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