Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of cell senescence and apoptosis in cyclophosphamide-induced premature ovarian failure in rats

31 Jul 2025

Abstract excerpt

BACKGROUND: Premature ovarian failure (POF) is a clinical condition characterized by a diminished ovarian reserve occurring before the age of 40, significantly affecting female reproductive health. However, its exact pathogenesis remains unclear. This research aimed to examine the mechanisms of cyclophosphamide (CTX)-induced senescence and apoptosis in the ovarian and cerebral cortex tissues of rats to provide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40745333
DOI: 10.1186/s13048-025-01759-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of cell senescence and apoptosis in cyclophosphamide-induced premature ovarian failure in ratsPMID 40745333Read ↗

Mechanisms of Cell Senescence and Apoptosis in Cyclophosphamide-Induced Premature Ovarian Failure in RatsSemantic proximity Read ↗

The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian InsufficiencySemantic proximity Read ↗

The role of cellular senescence in ovarian agingSemantic proximity Read ↗

Hydroxychloroquine Protects Against Cyclophosphamide-Induced Premature ovarian failure by Reducing Granulosa Cell Senescence via Regulation of the mtDNA-cGAS Signaling PathwaySemantic proximity Read ↗

Ovarian Aging: Molecular Mechanisms and Medical Management.Semantic proximity Read ↗

Positive and negative effects of cellular senescence during female reproductive aging and pregnancySemantic proximity Read ↗

The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventionsSemantic proximity Read ↗

Melatonin as Potential Targets for Delaying Ovarian AgingSemantic proximity Read ↗

Current understanding of ovarian aging.Semantic proximity Read ↗

Cell-free fat extract prevents diminished ovarian reserve by inhibiting granulosa cell senescenceSemantic proximity Read ↗

Mechanism of Platelet-Rich Plasma in Improving Cyclophosphamide-induced Premature Ovarian Failure in RatsSemantic proximity Read ↗

Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.