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Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants

1 Aug 2023

Abstract excerpt

Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance between ROS and antioxidants is disrupted, however, it can cause serious consequences of oxidative stress (OS), and the quantity and quality of oocytes will decline. Therefore, this review discusses the interrelationship between OS and...

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PMID: 37600717
DOI: 10.3389/fendo.2023.1172481

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