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Article

A clinico-genomic prognostic model for primary myelodysplastic neoplasm in Asia.

Blood cancer journal - 31 Jul 2025

Gill Harinder, Yim Rita, Lee Paul, Tsai Xavier Cheng-Hong, Li Vivian W K, Leung Garret M K, Ooi Melissa, Hui Tsz-Shing, Raghupathy Radha, Chin Lynn, Au Lester, Zhang Qi, Wu Tony K Y, Lee Carmen Y Y, Chng Wee-Joo, Tien Hwei-Fang, Hou Hsin-An, Kwong Yok-Lam

Abstract excerpt

A personalized prognostic model that takes into account the unique molecular features of primary myelodysplastic neoplasm (MDS) in Asia patients is lacking. Diagnostic clinicopathologic features, cytogenetic changes, and gene mutations of ethnic Asian patients with primary MDS were analyzed. Variables were evaluated for associations with overall survival (OS), leukemia-free survival (LFS), and time to progression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40745181
DOI: 10.1038/s41408-025-01339-0
PMCID: PMC12313991

Genes

GNAS
TP53
IDH2
NPM1
NRAS
PTPN11
RUNX1
SF3B1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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