Mayo Alliance Prognostic Model for Myelodysplastic Syndromes: Integration of Genetic and Clinical Information.

doi:10.1016/j.mayocp.2018.04.013

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Article

Mayo Alliance Prognostic Model for Myelodysplastic Syndromes: Integration of Genetic and Clinical Information.

Mayo Clinic proceedings - 1 Oct 2018

Tefferi Ayalew, Gangat Naseema, Mudireddy Mythri, Lasho Terra L, Finke Christy, Begna Kebede H, Elliott Michelle A, Al-Kali Aref, Litzow Mark R, Hook C Christopher, Wolanskyj Alexandra P, Hogan William J, Patnaik Mrinal M, Pardanani Animesh, Zblewski Darci L, He Rong, Viswanatha David, Hanson Curtis A, Ketterling Rhett P, Tang Jih-Luh, Chou Wen-Chien, Lin Chien-Chin, Tsai Cheng-Hong, Tien Hwei-Fang, Hou Hsin-An

Abstract excerpt

OBJECTIVE: To develop a new risk model for primary myelodysplastic syndromes (MDS) that integrates information on mutations, karyotype, and clinical variables. PATIENTS AND METHODS: Patients with World Health Organization-defined primary MDS seen at Mayo Clinic (MC) from December 28, 1994, through December 19, 2017, constituted the core study group. The National Taiwan University Hospital (NTUH) provided the...

Topics

Age Factors
Aged
Bone Marrow Examination
Core Binding Factor Alpha 2 Subunit
Female
Hemoglobins
Humans
Karyotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mutation

Myelodysplastic Syndromes

Phosphoproteins

Platelet Count

Prognosis

Proportional Hazards Models

RNA Splicing Factors

Repressor Proteins

Reproducibility of Results

Source

Open in PubMed

Identifiers

PMID: 29866419
DOI: 10.1016/j.mayocp.2018.04.013

Genes

ASXL1
RUNX1

Provenance

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