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Article

The molecular prognostic scoring system for normal karyotype myelodysplastic syndromes.

Journal of translational medicine - 16 Jan 2025

Wang Wei, Zhang Yudi, Yang Wenli, Liu Xiaozhen, Jiang Lingxu, Lang Wei, Luo Yingwan, Zhou Xinping, Wang Lu, Ye Li, Xu Ying, Ma Liya, Tong Hongyan

Abstract excerpt

BACKGROUND: Molecular-clinical prognostic models for Myelodysplastic syndromes (MDS) offer more accurate prognosis predictions, yet existing models often overlook the heterogeneity of mutational profiles against the cytogenetic background. Moreover, how to apply these models in regions where large panel NGS is unaffordable remains a significant challenge to be addressed. METHODS: A total of 237 NK MDS patients...

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Topics

Humans
Myelodysplastic Syndromes
Prognosis
Female
Male
Karyotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Aged

Middle Aged

Mutation

Karyotyping

Adult

Aged, 80 and over

Source

Open in PubMed Open full text

Identifiers

PMID: 39819628
DOI: 10.1186/s12967-024-05995-x
PMCID: PMC11740646

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