Article
Genetic and Epigenetic Biomarkers in Hypertension Impact on the Effectiveness of Individualized Therapy: A Systematic Review.
Journal of cardiovascular pharmacology - 1 Oct 2025
Silva Anderson Matheus Pereira da, Torres Elaine da Silva, Santos do Nascimento Maria da Vitória, Franco Julia Oliveira, Amaral Dillan Cunha, Corin Anderson Silva, Cavalcanti Lívia Barbosa, Maia Maria Bernadete de Sousa, de Souza Franco Eryvelton
Abstract excerpt
ABSTRACT: Arterial hypertension affects >1.28 billion adults globally, remaining a leading cause of cardiovascular morbidity and mortality. Despite effective therapies, suboptimal blood pressure control persists, highlighting the need for precision approaches. Epigenetic biomarkers, particularly DNA methylation (DNAm), have emerged as potential tools to enhance risk stratification and personalize antihypertensive...
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