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Involvement of NRF2 and AMPK signaling in aging and progeria: a digest

21 Jul 2025

Abstract excerpt

Aging refers to a gradual, continuous process of natural change which is accompanied by progressive loss in physiological functions and an increased risk of frailty, disease, and death. Cells face a declining capacity to adapt homeostasis after perturbation, resulting among others in an imbalance in reactive species production and damage removal, as well as in energy or nutrient sensing and usage. NRF2 (Nuclear...

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PMID: 40706292
DOI: 10.1016/j.redox.2025.103782

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