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Article

Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.

Journal of Crohn's & colitis - 10 May 2022

Luo Jiao, Xu Zhongwei, Noordam Raymond, van Heemst Diana, Li-Gao Ruifang

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have suggested a bidirectional association between depression and inflammatory bowel disease [IBD], including Crohn's disease [CD] and ulcerative colitis [UC]. However, it remains unclear whether the observed associations are causal due to the difficulties of determining sequential temporality. We investigated the association between depression and IBD by using...

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PMID: 34739073
DOI: 10.1093/ecco-jcc/jjab191

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