Identification of Genes Expressed by Human Airway Eosinophils after an In Vivo Allergen Challenge

Abstract excerpt

BACKGROUND: The mechanism for the contribution of eosinophils (EOS) to asthma pathophysiology is not fully understood. Genome-wide expression analysis of airway EOS by microarrays has been limited by the ability to generate high quality RNA from sufficient numbers of airway EOS. OBJECTIVE: To identify, by genome-wide expression analyses, a compendium of expressed genes characteristic of airway EOS following an in...

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