Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SERPINB10 promotes macrophage M2 polarization and airway inflammation in asthma

10 May 2025

Abstract excerpt

BACKGROUND: Macrophage M2 polarization plays a critical role in type 2 airway inflammation in asthma. We previously reported that serine peptidase inhibitor, clade B, member 10 (SERPINB10) promotes airway eosinophilic inflammation in asthma. OBJECTIVE: To investigate the role of SERPINB10 in macrophage M2 polarization and airway inflammation in asthma. METHODS: The expression of SERPINB10 was detected in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Immune cells in cancer
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40349036
DOI: 10.1186/s12931-025-03252-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SERPINB10 promotes macrophage M2 polarization and airway inflammation in asthmaPMID 40349036Read ↗

SERPINB10 Contributes to Asthma by Inhibiting the Apoptosis of Allergenic Th2 CellsSemantic proximity Read ↗

SERPINB10 contributes to asthma by inhibiting the apoptosis of allergenic Th2 cellsSemantic proximity Read ↗

MBD2-mediated Th17 differentiation in severe asthma is associated with impaired SOCS3 expressionSemantic proximity Read ↗

Title：IRAK-M has effects in regulation of lung epithelial inflammation through JNK and p38 MAPK pathwaysSemantic proximity Read ↗

M2 Macrophage Polarization and Its Role in Nasal Diseases: Signaling Pathways and Therapeutic ImplicationsSemantic proximity Read ↗

Inflammation in Asthma: Mechanistic Insights and the Role of Biologics in Therapeutic FrontiersSemantic proximity Read ↗

The presence and pathogenic roles of M(IL-33+IL-2) subset in allergic airway inflammationSemantic proximity Read ↗

Macrophage dysfunction in the pathogenesis and treatment of asthma.Semantic proximity Read ↗

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airwaysSemantic proximity Read ↗

TonEBP suppresses IL-10-mediated immunomodulation.Semantic proximity Read ↗

Macrophages in Ulcerative Colitis: Immunomodulatory Roles, Phenotypic Switching, and Therapeutic Targeting.Semantic proximity Read ↗

SOCS molecules: the growing players in macrophage polarization and functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.