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Article

SERPINB10 contributes to asthma by inhibiting the apoptosis of allergenic Th2 cells

14 Jun 2021

Abstract excerpt

BACKGROUND: Serine peptidase inhibitor, clade B, member 10 (SERPINB10) contributes to allergic inflammation in asthma. However, its role in the T-helper type 2 (Th2) response of allergic asthma is not known. The goal of this study was to unveil the function of SERPINB10 in the Th2 response of allergic asthma and the mechanism by which SERPINB10 affects the viability of Th2 cells. METHODS: Th2 cytokines and serum...

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PMID: 34126986
DOI: 10.1186/s12931-021-01757-1

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