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Article

Predisposition of IL-1β (-511 C/T) polymorphism to renal and hematologic disorders in Indian SLE patients.

Gene - 30 Jan 2018

Umare Vinod, Pradhan Vandana, Rajadhyaksha Anjali, Ghosh Kanjaksha, Nadkarni Anita

Abstract excerpt

OBJECTIVE: To see the role of IL-1β gene polymorphisms to disease susceptibility in Indian SLE patients. MATERIALS AND METHODS: This case-control study included 200 SLE patients and 201 controls. Serum levels of IL-1β and anti-C1q antibodies were measured by multiplex immunoassay and ELISA respectively. Genotyping of SNPs in IL-1β (-511C/T and +3954C/T) were performed by PCR-RFLP method. Autoantibody profile was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29032148
DOI: 10.1016/j.gene.2017.10.039

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