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Article

Genomic landscape and distinct molecular subtypes of primary testicular lymphoma.

Journal of translational medicine - 1 May 2024

Zhang Weilong, Yang Ping, Yang Yaru, Liu Shuozi, Xu Yongdeng, Wu Chaoling, Wang Jing, Liu Cuiling, Liu Hui, Li Shuangshuang, Huang Wei, Jing Hongmei

Abstract excerpt

Primary testicular lymphoma (PTL) is a rare lymphoma predominantly occurring in the elderly male population. It is characterized by a limited response to treatment and a heightened tendency towards relapse. Histologically, approximately 90% of PTL cases are classified as diffuse large B-cell lymphomas (DLBCL). Genetic features of PTL were delineated in a limited scope within several independent studies. Some of...

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Identifiers

PMID: 38693538
DOI: 10.1186/s12967-024-05140-8
PMCID: PMC11064289

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