Article
Modifications of coronary plaque phenotype on lipid-lowering therapies and risk of cardiovascular events: a systematic review and meta-regression analysis.
Atherosclerosis - 1 Mar 2026
Patti Giuseppe, Grisafi Leonardo, Azzolina Danila, Cumitini Luca, D'Amario Domenico, Mennuni Marco
Abstract excerpt
BACKGROUND AND AIMS: The specific relationship between changes in coronary plaque phenotype by optical coherence tomography (OCT) and decrease in major adverse cardiovascular events (MACE) among patients receiving lipid-lowering therapies (LLTs) is unknown. Aim was to quantify the relationship between LLTs-related improvement of coronary plaque phenotype (e.g. coronary plaque stabilization, as assessed by OCT)...
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