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Article

Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction.

JACC. Cardiovascular imaging - 1 Jul 2022

Nicholls Stephen J, Kataoka Yu, Nissen Steven E, Prati Francesco, Windecker Stephan, Puri Rishi, Hucko Thomas, Aradi Daniel, Herrman Jean-Paul R, Hermanides Renicus S, Wang Bei, Wang Huei, Butters Julie, Di Giovanni Giuseppe, Jones Stephen, Pompili Gianluca, Psaltis Peter J

Abstract excerpt

BACKGROUND: The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab produced coronary atheroma regression in statin-treated patients. OBJECTIVES: The purpose of this study was to determine the effect of evolocumab on optical coherence tomography (OCT) measures of plaque composition. METHODS: Patients with a non-ST-segment elevation myocardial infarction were treated with monthly evolocumab 420 mg...

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Share to Antibodies, Monoclonal, Humanized
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

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Source

Identifiers

PMID: 35431172
DOI: 10.1016/j.jcmg.2022.03.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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