Article
Comparison of the effects of pitavastatin versus pravastatin on coronary artery plaque phenotype assessed by tissue characterization using serial virtual histology intravascular ultrasound.
Heart and vessels - 1 Jan 2015
Nozue Tsuyoshi, Yamamoto Shingo, Tohyama Shinichi, Fukui Kazuki, Umezawa Shigeo, Onishi Yuko, Kunishima Tomoyuki, Sato Akira, Nozato Toshihiro, Miyake Shogo, Takeyama Youichi, Morino Yoshihiro, Yamauchi Takao, Muramatsu Toshiya, Hibi Kiyoshi, Terashima Mitsuyasu, Michishita Ichiro
Abstract excerpt
Thin-cap fibroatheroma (TCFA) is the most common type of vulnerable plaque and is the precursor of plaque rupture. However, rupture of a TCFA is not the only mechanism underlying thrombus formation or acute coronary syndrome. Although statin therapy changes the composition of coronary artery plaques, the effects of statins, particularly different types of statins, on plaque phenotype have not been fully examined....
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