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A Pair of DNA Aptamers That Can Selectively Bind to Bilirubin and Biliverdin

16 Jul 2025

Abstract excerpt

Bilirubin and biliverdin are two important metabolites from the degradation of heme. Development of aptamers for them will not only help with the measurement of their concentrations for diagnosing diseases such as neonatal jaundice and liver dysfunction, but may also aid in developing molecular switches for the regulation of gene expression. In this work, we report the selection of DNA aptamers against bilirubin...

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PMID: 40669049
DOI: 10.1021/acschembio.5c00438

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