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Article

Patients with anorexia nervosa have an increased burden of rare, damaging mutations in the BBOX1 gene

15 Jul 2025

Abstract excerpt

People with anorexia nervosa (AN) exhibit a strong aversion to eating calorically dense foods, especially those high in fat. It has previously been reported that these patients display altered metabolism of fatty acids, however it is unclear if these metabolic disturbances represent a primary biological substrate underlying predisposition to restrictive eating behaviors or occur secondarily to malnutrition. We...

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PMID: 40665398
DOI: 10.1186/s40337-025-01323-w

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