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Article

Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors.

PloS one - 1 Jan 2017

Lutter Michael, Bahl Ethan, Hannah Claire, Hofammann Dabney, Acevedo Summer, Cui Huxing, McAdams Carrie J, Michaelson Jacob J

Abstract excerpt

OBJECTIVE: Eating disorders develop through a combination of genetic vulnerability and environmental stress, however the genetic basis of this risk is unknown. METHODS: To understand the genetic basis of this risk, we performed whole exome sequencing on 93 unrelated individuals with eating disorders (38 restricted-eating and 55 binge-eating) to identify novel damaging variants. Candidate genes with an excessive...

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Identifiers

PMID: 28846695
DOI: 10.1371/journal.pone.0181556
PMCID: PMC5573281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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