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Article

Lack of CeR-2a RNA gene delays egg-laying onset in C. elegans mutant.

Biochemical and biophysical research communications - 8 Sept 2025

Koyama Takashi, Masui Tatsushi, Uematsu Tomoki, Ushida Chisato

Abstract excerpt

CeR-2a RNA is a putative Caenorhabditis elegans homolog of vertebrate U8 small nucleolar RNA (snoRNA), which plays an essential role in large subunit (LSU) pre-rRNA processing. It was previously reported that, in the mutant strain MT16939, which lacks the CeR-2a RNA gene (cer-2a), there were higher levels of accumulation of the LSU pre-rRNA c'1 than in wild-type N2. To confirm this, we generated two strains using...

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PMID: 40664083
DOI: 10.1016/j.bbrc.2025.152306

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