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Article

Long-term Survivors of Anaplastic Thyroid Cancer: A Genomic Predictive Model.

The Journal of clinical endocrinology and metabolism - 21 Jan 2026

Greenspun Benjamin C, Metzger Daniel Aryeh, Lee Sally, Pearson Bradley E, Li Jin H, Chen Shuibing, Zarnegar Rasa, Fahey Iii Thomas J, Finnerty Brendan M

Abstract excerpt

CONTEXT: Longer-term survival is possible for some patients with anaplastic thyroid cancer (ATC). However, genomic factors associated with improved survival are poorly characterized. OBJECTIVE: To develop a mathematical model to predict mutation-based survival risk in ATC. DESIGN: Retrospective cohort study of 204 ATC samples from the cBioPortal database, divided into 80% training and 20% validation cohorts....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40663630
DOI: 10.1210/clinem/dgaf391
PMCID: PMC13233113

Genes

BRAF
ATP10A
BSN
EGLN2
FLNC
FRAS1
MAPK12
MUC4
PIK3CA
PLD4
PNPLA2
RADIL
RECQL4
TET1
ZMYND8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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